A Total Eclipse of the Heart

A Total Eclipse of the Heart

Here is a cardiopharmaceutical take on the recent eclipse, which started in Mexico and moved northeast from Texas to Maine, and into eastern Canada, set to the tune of “Total Eclipse of the Heart” by Bonnie Tyler. Several medical treatments are associated with...
Mechanism X Factor

Mechanism X Factor

Much ink/many electrons have been spilled to explain the admittedly complex mechanisms of action for the small molecule, RRx-001 (nibrozetone). Applicable words and phrases are “NLRP3 inhibition,” “Nrf2 agonism,” “NO donation,” and “vascular normalization.” A more...
MMAdAPT-001

MMAdAPT-001

Modern day gladiators, the best mixed martial artists (MMAers) like Khabib Nurmagomedov, Jon Jones, Anderson Silva, Georges St-Pierre, and Fedor Emelianenko, shown above, are multidimensional, successfully combining stand up and ground-based combat to submit (“tap...
Anti-Inflammaging: A Modern-Day Fountain of Youth

Anti-Inflammaging: A Modern-Day Fountain of Youth

By: Bryan Oronsky, Ahad Javansalehi “Who wants to live forever?” -Freddie Mercury Introduction A common phrase that adults use with hyperactive children is “act your age!”. However, for hypoactive middle-aged and older adults, the best advice is “don’t act your age”....
EpicentRx Word of the Week: Aesculapian

EpicentRx Word of the Week: Aesculapian

“Aesculapian, heal thyself.” The caduceus (left) vs. the Rod of Aesculapius (right) Aesculapian adjective and noun es-kal-ay-pee-an Definition: adj: medical; medicinal. noun: a physician; doctor Example sentence: “In the story of Dr. Jekyll and Mr. Hyde, the main...