“Mad, Bad, and Dangerous to Know”

“Mad, Bad, and Dangerous to Know”

So said Lady Carolyn Lamb about her lover, the Romantic poet, aristocrat, infamous lady killer, and original rebel with a cause, Lord Byron. The same could be said of the hopefully soon-to-be-infamous tumor killer, AdAPT-001, an experimental oncolytic adenovirus which...
You Can’t Teach An Old Dogma New Tricks

You Can’t Teach An Old Dogma New Tricks

Or can you? This phrase, which comes from the legendary writer, Dorothy Parker, best known for her wicked wit and caustic repartee, highlights how dogma, referring to a well-accepted belief or set of beliefs, is so firmly fixed as to be unalterable. The dogma or...
EpicentRx Word of the Week (WOW): Diegesis

EpicentRx Word of the Week (WOW): Diegesis

“Is it called ‘indiegesistion’ when we hear upset stomach noises in a movie or on the TV”? Diegesis Definition (noun): 1. a narration 2. the fictional world of a novel or film Pronunciation: dahy-uh-jee-sis Diegetic Definition (adjective): anything that...
Bullet Blog #5: 4 Before and Then No More

Bullet Blog #5: 4 Before and Then No More

Celebrated American short-story writer and poet, Edgar Allan Poe, famously wrote, “Quoth the Raven ‘Nevermore.’” At EpicentRx we “quoth” the dosing regimen of RRx-001 (nibrozetone) in the Phase 2b KEVLARx clinical trial as “4 Before and Then No More.”...
Bullet Blog #4: Fast Facts About Cisplatin

Bullet Blog #4: Fast Facts About Cisplatin

First described by the Italian chemist Michele Peyrone in 1845, cisplatin is an alkylating agent that contains the metal platinum. Its full name is cis-diamminedichloroplatinum (II). Cisplatin is used to treat head and neck cancer as well as testicular, ovarian,...