Promising Safety and Efficacy Signals from a Small Phase 1 Pilot Study (PRIMETIME) with RRx-001 + Opdivo® [nivolumab] in Traditionally Checkpoint Inhibitor Non-Responsive Tumors

FORTRESS TUMOR: RRx-001 and AdAPT-001

  The maxim that “a man’s home is his castle” is made literal by tumors, which firmly entrench themselves behind castle-like barriers as a defense against the attritional war waged against them by chemotherapy, radiation, and immunotherapy. These barriers are...
The Debate About Daylight Saving Time Is A Snoozzze

The Debate About Daylight Saving Time Is A Snoozzze

On Sunday, March 12 at 2 a.m., don’t forget to advance your clocks forward one hour for Daylight Saving Time (DST). (Remember spring forward, fall back). This applies to most of the country, Hawaii, Arizona, Puerto Rico, Guam, and the U.S. Virgin Islands excepted....
All Killer, No Filler (AKNF)

All Killer, No Filler (AKNF)

In a TV review about a serial killer, we came across this pithy phrase: “all killer, no filler” (AKNF). AKNF denotes no extraneous content i.e., no filler, which perfectly encapsulates the minimalist design and effectiveness of the oncolytic adenovirus, AdAPT-001....
EpicentRx Explains: What is Anergy?

EpicentRx Explains: What is Anergy?

“Anergy” is a commonly used term in immuno-oncology, particularly in conjunction with T cells. So, what exactly does it mean and in what context is it used? The dictionary defines it as the “absence of the normal immune response to a particular antigen or allergen.” A...